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Understanding the Effect of Carbonate Ion on Cisplatin Binding to DNA
The role of carbonate in the binding of cis-diamminedichloroplatinum(II) to DNA was investigated in order to understand the potential involvement of carbonato-cisplatin species in the mechanism of action of platinum anticancer agents. Cisplatin was allowed to react with both double- and single-stran...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494524/ https://ncbi.nlm.nih.gov/pubmed/17465550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja071143p |
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