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Binding Interaction of HMGB4 with Cisplatin-Modified DNA

Proteins in the HMG family are important transcription factors. They recognize cisplatin-damaged DNA lesions with a structure-specific preference and account for more than 70% of all proteins that interact with the cisplatin 1,2-intrastrand d(GpG) cross-link. HMGB4, a new member of the mammalian HMG...

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Detalles Bibliográficos
Main Authors: Park, Semi, Lippard, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448822/
https://ncbi.nlm.nih.gov/pubmed/22901013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300649v
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