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TGFβ-induced RhoA activation and fibronectin production in mesangial cells require caveolae
Glomerular sclerosis of diverse etiologies is characterized by mesangial matrix accumulation, with transforming growth factor-β (TGFβ) an important pathogenic factor. The GTPase RhoA mediates TGFβ-induced matrix accumulation in some settings. Here we study the role of the membrane microdomain caveol...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494513/ https://ncbi.nlm.nih.gov/pubmed/18434385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00419.2007 |
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