Dual roles of parathyroid hormone related protein in TGF-β1 signaling and fibronectin up-regulation in mesangial cells

Little is known about the cross-talk between parathyroid hormone (PTH) related protein (PTHrP) and TGF-β1 in mesangial cells (MCs). Our results showed that PTHrP treatment (≤3 h) induced internalization of PTH1R (PTH/PTHrP receptor)–TβRII (TGF-β type 2 receptor) complex and suppressed TGF-β1-mediate...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Wu, Su-Zhen, Yang, Si-Jun, Chen, Hong-Min, Peng, Fang-Fang, Yu, Hong, Krepinsky, Joan C., Zhang, Bai-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665616/
https://ncbi.nlm.nih.gov/pubmed/28954822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20171061
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