Myristoylation of the poliovirus polyprotein is required for proteolytic processing of the capsid and for viral infectivity.
The poliovirus polyprotein is cotranslationally linked to myristic acid at its amino-terminal glycine residue. We investigated the role of myristoylation in the viral replication cycle by site-directed mutagenesis of this glycine codon. Synthetic full-length RNA transcripts carrying a Gly-to-Ala mut...
Kaydedildi:
| Yayımlandı: | J Virol |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1990
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249411/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157900/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.5.2433-2436.1990 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|