Collagen phagocytosis is regulated by the guanine nucleotide exchange factor Vav2

Collagen phagocytosis is a crucial α2β1-integrin-dependent process that mediates extracellular matrix remodeling by fibroblasts. We showed previously that after initial contact with collagen, activated Rac1 accelerates collagen phagocytosis but the Rac guanine nucleotide exchange factors (GEFs) that...

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Bibliographic Details
Main Authors: Arora, P. D., Marignani, P. A., McCulloch, C. A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
Subjects:
Extracellular Matrix, Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493554/
https://ncbi.nlm.nih.gov/pubmed/18434624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00168.2008
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