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Collagen phagocytosis is regulated by the guanine nucleotide exchange factor Vav2

Collagen phagocytosis is a crucial α2β1-integrin-dependent process that mediates extracellular matrix remodeling by fibroblasts. We showed previously that after initial contact with collagen, activated Rac1 accelerates collagen phagocytosis but the Rac guanine nucleotide exchange factors (GEFs) that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Arora, P. D., Marignani, P. A., McCulloch, C. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493554/
https://ncbi.nlm.nih.gov/pubmed/18434624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00168.2008
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