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CONTRIBUTION OF GUANINE NUCLEOTIDE EXCHANGE FACTOR-VAV(2) TO HYPERHOMOCYSTEINEMIC GLOMERULOSCLEROSIS IN RATS
We currently reported that Vav2, a member of the guanine nucleotide exchange factor (GEF)-Vav subfamily, participates in homocysteine (Hcys)-induced increases in Rac1 activity and consequent activation of NADPH oxidase in rat mesangial cells. However, the physiological relevance of this cellular act...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666012/ https://ncbi.nlm.nih.gov/pubmed/19029489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.115675 |
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