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CONTRIBUTION OF GUANINE NUCLEOTIDE EXCHANGE FACTOR-VAV(2) TO HYPERHOMOCYSTEINEMIC GLOMERULOSCLEROSIS IN RATS

We currently reported that Vav2, a member of the guanine nucleotide exchange factor (GEF)-Vav subfamily, participates in homocysteine (Hcys)-induced increases in Rac1 activity and consequent activation of NADPH oxidase in rat mesangial cells. However, the physiological relevance of this cellular act...

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Detalhes bibliográficos
Main Authors: Yi, Fan, Xia, Min, Li, Ningjun, Zhang, Chun, Tang, Lin, Li, Pin-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666012/
https://ncbi.nlm.nih.gov/pubmed/19029489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.115675
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