NMDA Receptor-Mediated Activation of NADPH Oxidase and Glomerulosclerosis in Hyperhomocysteinemic Rats

This study investigated the role of NMDA receptor in hyperhomocyteinemia (hHcys)-induced NADPH oxidase (Nox) activation and glomerulosclerosis. Sprague–Dawley rats were fed a folate-free (FF) diet to produce hHcys, and a NMDA receptor antagonist, MK-801, was administrated. Rats fed the FF diet exhib...

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Detalhes bibliográficos
Main Authors: Zhang, Chun, Yi, Fan, Xia, Min, Boini, Krishna M., Zhu, Qing, Laperle, Laura A., Abais, Justine M., Brimson, Christopher A., Li, Pin-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959176/
https://ncbi.nlm.nih.gov/pubmed/20406136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3091
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