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Epithelial-to-Mesenchymal Transition in Podocytes Mediated by Activation of NADPH Oxidase in Hyperhomocysteinemia

The present study tested the hypothesis that hyperhomocysteinemia (hHcys) induces podocytes to undergo epithelial-to-mesenchymal transition (EMT) through the activation of NADPH oxidase (Nox). It was found that increased homocysteine (Hcys) level suppressed the expression of slit diaphragm-associate...

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Detalhes bibliográficos
Main Authors: Zhang, Chun, Xia, Min, Boini, Krishna M., Li, Cai-Xia, Abais, Justine M., Li, Xiao-Xue, Laperle, Laura A., Li, Pin-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299405/
https://ncbi.nlm.nih.gov/pubmed/21647593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-011-0981-y
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