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ACTIVATION OF NALP3 INFLAMMASOMES TURNS ON PODOCYTE INJURY AND GLOMERULAR SCLEROSIS IN HYPERHOMOCYSTEINEMIA

Inflammasome is a multiprotein complex consisting of Nod-like receptor protein 3 (NALP 3), apoptosis-associated speck-like protein (ASC), and caspase-1 or 5, which functions to switch on the inflammatory process. The present study hypothesized that the formation and activation of NALP3 inflammasomes...

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Detalhes bibliográficos
Main Authors: Zhang, Chun, Boini, Krishna M., Xia, Min, Abais, Justine M., Li, Xiang, Liu, Qinglian, Li, Pin-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753400/
https://ncbi.nlm.nih.gov/pubmed/22647887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.189688
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