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c-Cbl-Dependent Monoubiquitination and Lysosomal Degradation of gp130
Interleukin 6 (IL-6), a pleiotropic cytokine, functions in cells through its interaction with its receptor complex, which consists of two ligand-binding α subunits and two signal-transducing subunits known as gp130. There is a wealth of studies on signals mediated by gp130, but its downregulation is...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493370/ https://ncbi.nlm.nih.gov/pubmed/18519587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01784-07 |
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