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Mechanistic Studies of a T20-Dependent Human Immunodeficiency Virus Type 1 Variant

We previously described a T20-dependent human immunodeficiency virus type 1 variant from a patient on T20 therapy (3). This virus carries two mutations in the gp41 domain of the envelope protein (Env) that was proposed to undergo a premature conformational switch to the 6-helix bundle structure. The...

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Autors principals: Baldwin, Chris, Berkhout, Ben
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493336/
https://ncbi.nlm.nih.gov/pubmed/18480456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02524-07
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