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Genetic Instability of Live, Attenuated Human Immunodeficiency Virus Type 1 Vaccine Strains

Live, attenuated viruses have been the most successful vaccines in monkey models of human immunodeficiency virus type 1 (HIV-1) infection. However, there are several safety concerns about using such an anti-HIV vaccine in humans, including reversion of the vaccine strain to virulence and recombinati...

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Detalhes bibliográficos
Main Authors: Berkhout, Ben, Verhoef, Koen, van Wamel, Jeroen L. B., Back, Nicole K. T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC103934/
https://ncbi.nlm.nih.gov/pubmed/9882315
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