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Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys

<p>Abstract</p> <p>Background</p> <p>The cytidine deaminases APOBEC3G (A3G) and APOBEC3F (A3F) are innate cellular factors that inhibit replication of a number of viruses, including HIV-1. Since antiviral activity of APOBEC3 has been mainly confirmed by <it>in vitro </it>data, we examined their role...

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Principais autores: Stahl-Hennig Christiane, Motzkus Dirk, Sauermann Ulrike, Mußil Bianka, Sopper Sieghart
Format: Artigo
Jezik:Inglês
Izdano: BMC 2011-09-01
Serija:Retrovirology
Online dostop:http://www.retrovirology.com/content/8/1/77
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