Genetic Instability of Live, Attenuated Human Immunodeficiency Virus Type 1 Vaccine Strains

Live, attenuated viruses have been the most successful vaccines in monkey models of human immunodeficiency virus type 1 (HIV-1) infection. However, there are several safety concerns about using such an anti-HIV vaccine in humans, including reversion of the vaccine strain to virulence and recombinati...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Berkhout, Ben, Verhoef, Koen, van Wamel, Jeroen L. B., Back, Nicole K. T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103934/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1138-1145.1999
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