Herpes Simplex Virus Type 1 ICP27 Regulates Expression of a Variant, Secreted Form of Glycoprotein C by an Intron Retention Mechanism

We previously showed that herpes simplex virus type 1 (HSV-1) immediate-early (IE) protein ICP27 can posttranscriptionally stimulate mRNA accumulation from a transfected viral late gene encoding glycoprotein C (gC) (K. D. Perkins, J. Gregonis, S. Borge, and S. A. Rice, J. Virol. 77:9872-9884, 2003)....

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Autors principals: Sedlackova, Lenka, Perkins, Keith D., Lengyel, Joy, Strain, Anna K., van Santen, Vicky L., Rice, Stephen A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493323/
https://ncbi.nlm.nih.gov/pubmed/18495765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00388-08
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