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Functional Comparison of Herpes Simplex Virus 1 (HSV-1) and HSV-2 ICP27 Homologs Reveals a Role for ICP27 in Virion Release

Numerous studies have focused on the regulatory functions of ICP27, an immediate-early (IE) protein of herpes simplex virus 1 (HSV-1). However, its homolog in HSV-2, termed ICP27t2, has been little studied. Here, we used two different approaches to functionally compare ICP27t2 and ICP27. In transfec...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Park, Donglim, Lalli, Joseph, Sedlackova-Slavikova, Lenka, Rice, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325737/
https://ncbi.nlm.nih.gov/pubmed/25540385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02994-14
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