Mutation of a consensus purine nucleotide binding site in the adeno-associated virus rep gene generates a dominant negative phenotype for DNA replication.

Lignende værker

• In vitro resolution of adeno-associated virus DNA hairpin termini by wild-type Rep protein is inhibited by a dominant-negative mutant of rep.
  af: Owens, R A, et al.
  Udgivet: (1992)
• Cell lines inducibly expressing the adeno-associated virus (AAV) rep gene: requirements for productive replication of rep-negative AAV mutants.
  af: Hölscher, C, et al.
  Udgivet: (1994)
• Adeno-Associated Virus Type 2 Rep68 Can Bind to Consensus Rep-Binding Sites on the Herpes Simplex Virus 1 Genome
  af: Seyffert, Michael, et al.
  Udgivet: (2015)
• Negative regulation of the adeno-associated virus (AAV) P5 promoter involves both the P5 rep binding site and the consensus ATP-binding motif of the AAV Rep68 protein.
  af: Kyöstiö, S R, et al.
  Udgivet: (1995)
• Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levels.
  af: Kyöstiö, S R, et al.
  Udgivet: (1994)