Interaction of wild-type and mutant adeno-associated virus (AAV) Rep proteins on AAV hairpin DNA.

Both the Rep68 and Rep78 proteins of adeno-associated virus type 2 (AAV) bind to AAV terminal repeat hairpin DNA and can mediate site-specific nicking in vitro at the terminal resolution site (trs) within the terminal repeats. To define the regions of the Rep proteins required for these functions, a...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Weitzman, M D, Kyöstiö, S R, Carter, B J, Owens, R A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190087/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8642672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.4.2440-2448.1996
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