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Interaction of wild-type and mutant adeno-associated virus (AAV) Rep proteins on AAV hairpin DNA.

Both the Rep68 and Rep78 proteins of adeno-associated virus type 2 (AAV) bind to AAV terminal repeat hairpin DNA and can mediate site-specific nicking in vitro at the terminal resolution site (trs) within the terminal repeats. To define the regions of the Rep proteins required for these functions, a...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Weitzman, M D, Kyöstiö, S R, Carter, B J, Owens, R A
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190087/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8642672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.4.2440-2448.1996
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