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Costimulatory effects of IL-1 on the expansion/differentiation of CD4(+)CD25(+)Foxp3(+) and CD4(+)CD25(+)Foxp3(–) T cells
CD4(+)CD25(+)forkhead box p3 (Foxp3)(+) regulatory T cells (Treg) control peripheral tolerance. Although Treg are anergic when stimulated through the TCR, mature bone marrow-derived, but not splenic, dendritic cells (DC) can induce their proliferation after TCR stimulation in the absence of IL-2. On...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Society for Leukocyte Biology
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493074/ https://ncbi.nlm.nih.gov/pubmed/18477692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0208085 |
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