SerpinB1 regulates homeostatic expansion of IL-17(+) γδ and CD4(+) Th17 cells

SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Although loss of serpinB1 in mice does not result in gross immune deregulation, serpinb1a(−/−) mice display increased mortality and inflammation-associated morbidity upon chal...

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Main Authors: Zhao, Picheng, Hou, Lifei, Farley, Kalamo, Sundrud, Mark S., Remold-O'Donnell, Eileen
Format: Artigo
Jezik:Inglês
Izdano: Society for Leukocyte Biology 2014
Teme:
Inflammation, Extracellular Mediators, & Effector Molecules
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923080/
https://ncbi.nlm.nih.gov/pubmed/24249741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0613331
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