In vivo expansion of CD4(+)CD45RO–CD25(+) T cells expressing foxP3 in IL-2-treated HIV-infected patients

Administration of IL-2 to HIV-infected patients leads to expansion of a unique subset of CD4(+)CD45RO(–)CD25(+) cells. In this study, the origin, clonality, and function of these cells were investigated. Analysis of TCR excision circles revealed that the CD4(+)CD45RO(–)CD25(+) cells were the product...

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Autores principales: Sereti, Irini, Imamichi, Hiromi, Natarajan, Ven, Imamichi, Tomozumi, Ramchandani, Meena S., Badralmaa, Yunden, Berg, Steve C., Metcalf, Julia A., Hahn, Barbara K., Shen, Jean M., Powers, April, Davey, Richard T., Kovacs, Joseph A., Shevach, Ethan M., Lane, H. Clifford
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2005
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142113/
https://ncbi.nlm.nih.gov/pubmed/15937547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24307
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