Increased peripheral expansion of naive CD4+ T cells in vivo after IL-2 treatment of patients with HIV infection

Intermittent interleukin-2 (IL-2) therapy has been shown to increase the number of CD4+ T cells, preferentially cells with a naive phenotype, in patients with HIV infection. For this report we investigated the mechanism underlying this expansion by studying the relative roles of peripheral expansion...

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Autori principali: Natarajan, Ven, Lempicki, Richard A., Sereti, Irini, Badralmaa, Yunden, Adelsberger, Joseph W., Metcalf, Julia A., Prieto, Darue A., Stevens, Randy, Baseler, Michael W., Kovacs, Joseph A., Lane, H. Clifford
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125022/
https://ncbi.nlm.nih.gov/pubmed/12149467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162352399
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