Ładuje się......
Disruption of the homeostatic balance between autoaggressive (CD4(+)CD40(+)) and regulatory (CD4(+)CD25(+)FoxP3(+)) T cells promotes diabetes
Although regulatory T cells (Tregs) are well described, identifying autoaggressive effector T cells has proven more difficult. However, we identified CD4(lo)CD40(+) (Th40) cells as being necessary and sufficient for diabetes in the NOD mouse model. Importantly, these cells are present in pancreata o...
Zapisane w:
| Główni autorzy: | , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Society for Leukocyte Biology
2008
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493071/ https://ncbi.nlm.nih.gov/pubmed/18469093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1207857 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|