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Human fatty acid synthase: Assembling recombinant halves of the fatty acid synthase subunit protein reconstitutes enzyme activity

Our model of the native fatty acid synthase (FAS) depicts it as a dimer of two identical multifunctional proteins (M(r) ≈ 272,000) arranged in an antiparallel configuration so that the active Cys-SH of the β-ketoacyl synthase of one subunit (where the acyl group is attached) is juxtaposed within 2 Å...

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Detaylı Bibliyografya
Asıl Yazarlar: Jayakumar, Arumugam, Chirala, Subrahmanyam S., Wakil, Salih J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences of the USA 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC24928/
https://ncbi.nlm.nih.gov/pubmed/9356448
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