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Site-specific mutagenesis of a highly conserved region of the herpes simplex virus type 1 DNA polymerase gene.

Seven point mutations were introduced into region I of the herpes simplex virus type 1 DNA polymerase, which is most highly conserved among DNA polymerases and has no drug sensitivity markers mapped to it. The functional consequences of these mutations were studied in an in vitro transcription-trans...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Dorsky, D I, Crumpacker, C S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249264/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2154619/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.3.1394-1397.1990
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