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Site-specific mutagenesis of a highly conserved region of the herpes simplex virus type 1 DNA polymerase gene.

Seven point mutations were introduced into region I of the herpes simplex virus type 1 DNA polymerase, which is most highly conserved among DNA polymerases and has no drug sensitivity markers mapped to it. The functional consequences of these mutations were studied in an in vitro transcription-trans...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Virol
Principais autores: Dorsky, D I, Crumpacker, C S
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 1990
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249264/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2154619/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.3.1394-1397.1990
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