Site-specific mutagenesis of a highly conserved region of the herpes simplex virus type 1 DNA polymerase gene.

Seven point mutations were introduced into region I of the herpes simplex virus type 1 DNA polymerase, which is most highly conserved among DNA polymerases and has no drug sensitivity markers mapped to it. The functional consequences of these mutations were studied in an in vitro transcription-trans...

Полное описание

Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Dorsky, D I, Crumpacker, C S
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1990
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249264/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2154619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.3.1394-1397.1990
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