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RIG-I plays a critical role in negatively regulating granulocytic proliferation
RIG-I has been implicated in innate immunity by sensing intracellular viral RNAs and inducing type I IFN production. However, we have found a significant RIG-I induction in a biological setting without active viral infection—namely, during RA-induced terminal granulocytic differentiation of acute my...
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| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2492484/ https://ncbi.nlm.nih.gov/pubmed/18650396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804895105 |
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