RA-inducible gene-I induction augments STAT1 activation to inhibit leukemia cell proliferation

RA-inducible gene I (RIG-I/DDX58) has been shown to activate IFN-β promoter stimulator 1 (IPS-1) on recognizing cytoplasmic viral RNAs. It is unclear how RIG-I functions within the IFN and/or RA signaling process in acute myeloid leukemia (AML) cells, however, where obvious RIG-I induction is observ...

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Detalhes bibliográficos
Main Authors: Jiang, Lin-Jia, Zhang, Nan-Nan, Ding, Fei, Li, Xian-Yang, Chen, Lei, Zhang, Hong-Xin, Zhang, Wu, Chen, Sai-Juan, Wang, Zhu-Gang, Li, Jun-Min, Chen, Zhu, Zhu, Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033283/
https://ncbi.nlm.nih.gov/pubmed/21224412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019059108
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