Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells

Pregnancy in rodents is associated with a two- to threefold increase in β-cell mass, which is attributable to large increases in β-cell proliferation, complimented by increases in β-cell size, survival, and function and mediated mainly by the lactogenic hormones prolactin (PRL) and placental lactoge...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Chen, Hainan, Kleinberger, Jeffrey W., Takane, Karen K., Salim, Fatimah, Fiaschi-Taesch, Nathalie, Pappas, Kyrie, Parsons, Ramon, Jiang, Jing, Zhang, Yue, Liu, Hongtao, Wang, Peng, Bender, Aaron S., Frank, Stuart J., Stewart, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2015
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613973/
https://ncbi.nlm.nih.gov/pubmed/26159175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0083
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