Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

OBJECTIVE: Most knowledge on human β-cell cycle control derives from immunoblots of whole human islets, mixtures of β-cells and non-β-cells. We explored the presence, subcellular localization, and function of five early G1/S phase molecules—cyclins D1–3 and cdk 4 and 6—in the adult human β-cell. RES...

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Detalhes bibliográficos
Main Authors: Fiaschi-Taesch, Nathalie M., Salim, Fatimah, Kleinberger, Jeffrey, Troxell, Ronnie, Cozar-Castellano, Irene, Selk, Karen, Cherok, Edward, Takane, Karen K., Scott, Donald K., Stewart, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911074/
https://ncbi.nlm.nih.gov/pubmed/20668294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1776
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