Rig-I regulates NF-κB activity through binding to Nf-κb1 3′-UTR mRNA

Retinoic acid inducible gene I (RIG-I) senses viral RNAs and triggers innate antiviral responses through induction of type I IFNs and inflammatory cytokines. However, whether RIG-I interacts with host cellular RNA remains undetermined. Here we report that Rig-I interacts with multiple cellular mRNAs...

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Autori principali: Zhang, Hong-Xin, Liu, Zi-Xing, Sun, Yue-Ping, Zhu, Jiang, Lu, Shun-Yuan, Liu, Xue-Song, Huang, Qiu-Hua, Xie, Yin-Yin, Zhu, Hou-Bao, Dang, Su-Ying, Chen, Hai-Feng, Zheng, Guang-Yong, Li, Yi-Xue, Kuang, Ying, Fei, Jian, Chen, Sai-Juan, Chen, Zhu, Wang, Zhu-Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631665/
https://ncbi.nlm.nih.gov/pubmed/23553835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304432110
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