Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling

Aging is the greatest independent risk factor for the occurrence of stroke and poor outcomes, at least partially through progressive increases in oxidative stress and inflammation with advanced age. Klotho is an antiaging gene, the expression of which declines with age. Klotho may protect against ne...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Zhou, Hong-Jing, Li, Hui, Shi, Meng-Qi, Mao, Xiao-Na, Liu, Dong-Ling, Chang, Yi-Ran, Gan, Yu-Miao, Kuang, Xi, Du, Jun-Rong
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778393/
https://ncbi.nlm.nih.gov/pubmed/29403373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00950
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