Transcription of the S gene in transgenic mice is associated with hypomethylation at specific sites and with DNase I sensitivity.
The methylation status of hepatitis B virus (HBV) DNA was investigated in different organs from two strains of transgenic mice (E36 and E11) expressing the hepatitis B surface antigen (HBsAg) gene specifically in the liver. Specific sites in the S gene were shown to be methylated in all the organs o...
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| 發表在: | J Virol |
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| Principais autores: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
1990
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249193/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2296089/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.931-935.1990 |
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