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Transcription of the S gene in transgenic mice is associated with hypomethylation at specific sites and with DNase I sensitivity.

The methylation status of hepatitis B virus (HBV) DNA was investigated in different organs from two strains of transgenic mice (E36 and E11) expressing the hepatitis B surface antigen (HBsAg) gene specifically in the liver. Specific sites in the S gene were shown to be methylated in all the organs o...

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Bibliografske podrobnosti
Main Authors: Pourcel, C, Tiollais, P, Farza, H
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC249193/
https://ncbi.nlm.nih.gov/pubmed/2296089
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