TGF-β Receptor Blockade Augments the Effectiveness of Adoptive T-Cell Therapy of Established Solid Cancers

PURPOSE: Adoptive cellular immunotherapy has promise as an approach to eradicate established tumors. However, a significant hurdle in the success of cellular immunotherapy involves recently identified mechanisms of immune suppression on cytotoxic T-cells at the effector phase. Transforming growth fa...

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Bibliografiske detaljer
Main Authors: Wallace, Africa, Kapoor, Veena, Sun, Jing, Mrass, Paul, Weninger, Wolfgang, Heitjan, Daniel F., June, Carl, Kaiser, Larry R., Ling, Leona E., Albelda, Steven M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491721/
https://ncbi.nlm.nih.gov/pubmed/18559619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0356
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