Using macrophage activation to augment immunotherapy of established tumours

BACKGROUND: Successful immunotherapy will require alteration of the tumour microenvironment and/or decreased immune suppression. Tumour-associated macrophages (TAMs) are one major factor affecting tumour microenvironment. We hypothesised that altering TAM phenotype would augment the efficacy of immu...

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Detalhes bibliográficos
Main Authors: Fridlender, Z G, Jassar, A, Mishalian, I, Wang, L-CS, Kapoor, V, Cheng, G, Sun, J, Singhal, S, Levy, L, Albelda, S M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619255/
https://ncbi.nlm.nih.gov/pubmed/23481183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.93
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