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TGF-β Receptor Blockade Augments the Effectiveness of Adoptive T-Cell Therapy of Established Solid Cancers
PURPOSE: Adoptive cellular immunotherapy has promise as an approach to eradicate established tumors. However, a significant hurdle in the success of cellular immunotherapy involves recently identified mechanisms of immune suppression on cytotoxic T-cells at the effector phase. Transforming growth fa...
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Huvudupphovsmän: | , , , , , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
2008
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2491721/ https://ncbi.nlm.nih.gov/pubmed/18559619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0356 |
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