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Conservation and Variability of Dengue Virus Proteins: Implications for Vaccine Design

BACKGROUND: Genetic variation and rapid evolution are hallmarks of RNA viruses, the result of high mutation rates in RNA replication and selection of mutants that enhance viral adaptation, including the escape from host immune responses. Variability is uneven across the genome because mutations resu...

詳細記述

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書誌詳細
主要な著者: Khan, Asif M., Miotto, Olivo, Nascimento, Eduardo J. M., Srinivasan, K. N., Heiny, A. T., Zhang, Guang Lan, Marques, E. T., Tan, Tin Wee, Brusic, Vladimir, Salmon, Jerome, August, J. Thomas
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491585/
https://ncbi.nlm.nih.gov/pubmed/18698358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000272
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