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Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis

BACKGROUND: The identification of mutations that confer unique properties to a pathogen, such as host range, is of fundamental importance in the fight against disease. This paper describes a novel method for identifying amino acid sites that distinguish specific sets of protein sequences, by compara...

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Detalhes bibliográficos
Main Authors: Miotto, Olivo, Heiny, AT, Tan, Tin Wee, August, J Thomas, Brusic, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259419/
https://ncbi.nlm.nih.gov/pubmed/18315849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-S1-S18
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