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Structural basis for hygromycin B inhibition of protein biosynthesis
Aminoglycosides are one of the most widely used and clinically important classes of antibiotics that target the ribosome. Hygromycin B is an atypical aminoglycoside antibiotic with unique structural and functional properties. Here we describe the structure of the intact Escherichia coli 70S ribosome...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2491480/ https://ncbi.nlm.nih.gov/pubmed/18567815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1076908 |
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