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Hygromycin B inhibits synthesis of murine coronavirus RNA.

The aminoglycoside hygromycin B inhibits the infection of mouse hepatitis virus (MHV) A59 both in vitro and in vivo. In probing the mechanism by which hygromycin B exerts its antiviral effect, we describe here studies which point to inhibition of viral RNA synthesis as the key step in virus replicat...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Macintyre, G, Woods, D E, Anderson, R
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245443/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1667257/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.12.2630
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