Hygromycin B resistance mediates elimination of Leishmania virus from persistently infected parasites.

A series of pX63-HYG derivatives encoding Leishmania RNA virus 1-4 (LRV1-4) sequences were electroporated into cells of Leishmania strain M4147, a virus-infected strain of L. guyanensis. After 6 weeks of drug selection (hygromycin B), transfected parasites lacked detectable quantities of viral genom...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ro, Y T, Scheffter, S M, Patterson, J L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.8991-8998.1997
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