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Structural basis for hygromycin B inhibition of protein biosynthesis

Aminoglycosides are one of the most widely used and clinically important classes of antibiotics that target the ribosome. Hygromycin B is an atypical aminoglycoside antibiotic with unique structural and functional properties. Here we describe the structure of the intact Escherichia coli 70S ribosome...

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Sonraí Bibleagrafaíochta
Main Authors: Borovinskaya, Maria A., Shoji, Shinichiro, Fredrick, Kurt, Cate, Jamie H.D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491480/
https://ncbi.nlm.nih.gov/pubmed/18567815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1076908
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