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Hygromycin B Inhibition of Protein Synthesis and Ribosome Biogenesis in Escherichia coli
The aminoglycoside antibiotic hygromycin B was examined in Escherichia coli cells for inhibitory effects on translation and ribosomal-subunit formation. Pulse-chase labeling experiments were performed, which verified lower rates of ribosomal-subunit synthesis in drug-treated cells. Hygromycin B exhi...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797780/ https://ncbi.nlm.nih.gov/pubmed/17043113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01116-06 |
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