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Hygromycin B Inhibition of Protein Synthesis and Ribosome Biogenesis in Escherichia coli

The aminoglycoside antibiotic hygromycin B was examined in Escherichia coli cells for inhibitory effects on translation and ribosomal-subunit formation. Pulse-chase labeling experiments were performed, which verified lower rates of ribosomal-subunit synthesis in drug-treated cells. Hygromycin B exhi...

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Bibliographische Detailangaben
Hauptverfasser: McGaha, Susan M., Champney, W. Scott
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797780/
https://ncbi.nlm.nih.gov/pubmed/17043113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01116-06
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