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RNA-peptide fusions for the in vitro selection of peptides and proteins

Covalent fusions between an mRNA and the peptide or protein that it encodes can be generated by in vitro translation of synthetic mRNAs that carry puromycin, a peptidyl acceptor antibiotic, at their 3′ end. The stable linkage between the informational (nucleic acid) and functional (peptide) domains...

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Detalles Bibliográficos
Main Authors: Roberts, Richard W., Szostak, Jack W.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences of the USA 1997
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC24913/
https://ncbi.nlm.nih.gov/pubmed/9356443
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