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Identification within the simian virus 40 genome of a chromosomal loop attachment site that contains topoisomerase II cleavage sites.

We demonstrate that the simian virus 40 genome contains a single MAR (matrix association region) that maps within a large T-antigen coding region (nucleotides 4071 to 4377). This region contains topoisomerase II cleavage sites, exhibits sequence similarity with cellular MARs, and recognizes the same...

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Publicat a:J Virol
Autors principals: Pommier, Y, Cockerill, P N, Kohn, K W, Garrard, W T
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1990
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249119/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2152827/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.1.419-423.1990
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